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Profile summary

Bryan Wise is an award-winning technology executive and the first CIO at 6sense, where he is responsible for orchestrating transformative change across IT, security, business systems, and company-wide automation.

With a reputation for driving strategic IT alignment and cross-functional innovation, Bryan’s leadership has helped modern SaaS organisations scale securely and intelligently. At 6sense, he has spearheaded major initiatives that blend automation, security, and customer-centric innovation, making the IT function a true enabler of business growth.

His career includes IT leadership roles at GitLab, DocuSign, and Snowflake, where he built scalable systems in hypergrowth environments.

Connect with Bryan on: LinkedIn

Career highlights 

2022
Chief Information Officer
2020
Chief Information Officer
2018
VP & Head of IT,
2014
VP of Global IT Ops & Infra
2006
Director of IT
2000
Manager of IT

Claim to fame

The AI automation leader

Bryan launched the “Automation Domination” initiative at 6sense, which aimed to eliminate repetitive manual work across departments using AI and automation tools. The initiative saved over 91,000 hours of manual labor across the organization, surpassing initial objectives by nearly 50%. This award-winning effort earned the company a benchmark in internal automation-led efficiency.

The revenue-centric CIO

Bryan Wise has redefined what innovation means for IT leaders by embedding the CIO function across the entire revenue cycle, from demand generation to deal closure. At 6sense, he championed a lead-to-cash transformation powered by AI and machine learning, proving that IT isn’t just a backend enabler but a front-line growth driver.

The alignment architect

Bryan Wise is on a mission to turn sales and marketing into the high-performing power duo every go-to-market team aspires to be. At 6sense, he has championed the use of shared technology and AI-powered insights to eliminate misalignment across revenue teams, transforming fractured customer journeys into coordinated, high-impact engagement. His approach replaces gut-driven decisions with a unified data layer, ensuring that sales and marketing operate from a single source of truth.

Bryan's AI philosophy

Bryan Wise
CIO of 6sense 

"Trust in AI grows over time. As we continue working with AI agents under human oversight, we’ll build enough trust to gradually hand over more autonomy. This balance of AI automation with human oversight is how we build a sustainable, trust-based partnership with AI." Source

“If you don’t embrace the change, you will be a laggard. Because this change is happening with or without you.” Source

“By prioritizing the customer in every tech decision, CIOs can spearhead the transformation toward a business model where technology serves as the backbone of customer engagement and satisfaction. This approach addresses the immediate challenge of aligning tech and business strategies.” Source

Awards and accolades

BayAreaCIO ORBIE Awards – Corporate Winner – 2024
CIO 100 Award Winner – 2024

What does it take to be an AI Champion? 

We’re not looking for trophies. We’re looking for trailblazers.

You’re an AI Champion, if you’ve: 
Implemented AI in the real world not a pitch deck.
Driven change across teams, even when it wasn’t easy.
Led from the front, helping your org rethink how work gets done. 
Sounds like something you’re doing right now? 

Tell us about your AI work